What is ICD-10 code F25?

F25 is the ICD-10-CM category for Schizoaffective disorders, in the F20 to F29 block (Schizophrenia, schizotypal, delusional, and other non-mood psychotic disorders). It is not billable on its own; claims use one of its four child codes, which name the type of mood episode.

Is F25 a billable ICD-10-CM code?

No. In the FY2027 ICD-10-CM code set (effective October 1, 2026), F25 is a category header. The billable codes are F25.0 (Schizoaffective disorder, bipolar type), F25.1 (Schizoaffective disorder, depressive type), F25.8 (Other schizoaffective disorders), and F25.9 (Schizoaffective disorder, unspecified).

What is the difference between F25.0 and F25.1?

F25.0 (bipolar type) is used when a manic episode is part of the presentation; major depressive episodes may also occur. The tabular list includes "Cyclic schizophrenia" and the manic and mixed types under F25.0. F25.1 (depressive type) is used when only major depressive episodes are part of the presentation.

F25.9 (Schizoaffective disorder, unspecified) is for schizoaffective disorder documented without the type; the tabular list includes "Schizoaffective psychosis NOS" under it, and the Alphabetic Index sends "Disorder, schizoaffective" with no further detail to F25.9. Under the official guidelines, F25.8 is for a documented presentation that has no specific code, and F25.9 is for one documented without that detail.

What are the diagnostic criteria for schizoaffective disorder?

A major mood episode (depressive or manic) occurs together with the symptoms of schizophrenia. Delusions or hallucinations must also be present for 2 weeks or more without a major mood episode at some point in the lifetime course, and symptoms of a major mood episode must be present for the majority of the total duration of the illness, including active and residual phases.

What is the difference between schizoaffective disorder and schizophrenia?

The Merck Manual distinguishes schizoaffective disorder from schizophrenia by the coexistence of a major depressive or manic episode. Category F20 (Schizophrenia) carries an Excludes1 note for schizoaffective disorder (F25.-), so the two are not coded together.

What is the difference between F25 and a mood disorder with psychotic features?

Category F25 carries an Excludes1 note for mood disorders with psychotic symptoms (F30.2, F31.2, F31.5, F31.64, F32.3, F33.3). In those disorders, psychosis occurs only during mood episodes. Schizoaffective disorder requires psychotic symptoms for at least 2 weeks without a mood episode. Telling them apart may require following the symptoms over time.

What scale is used with F25?

There is no single screening test that diagnoses schizoaffective disorder. Clinician-rated scales such as the Brief Psychiatric Rating Scale (BPRS) measure the breadth and severity of psychotic and mood symptoms and are useful for tracking change once care begins. A depression measure such as the PHQ-9 can track the depressive component.

How is schizoaffective disorder treated?

According to the Merck Manual, treatment combines antipsychotic and/or antidepressant medication, psychotherapy, and community support. For the bipolar (manic) type, a second-generation antipsychotic may be enough, with a mood stabilizer added if needed. For the depressive type, an antidepressant may be added once psychotic symptoms are stable, with SSRIs preferred for their safety profile.

F25ICD-10-CMSchizoaffective Disorder

Official ICD-10-CM descriptor: Schizoaffective disorders · Category header, not billable: use a more specific code

A psychotic disorder in which a major depressive or manic episode occurs together with symptoms of schizophrenia, with delusions or hallucinations for at least 2 weeks without a mood episode, and mood symptoms present for most of the illness.

F25 at a glance

ICD-10-CM F25
Psychotic
Category header, not billable: use a more specific code
Recommended screener
Brief Psychiatric Rating Scale (BPRS)
View scale
Billing the screening
In the US, administering and scoring the scale usually bills under CPT 96127; the session itself under 90791 or 90834/90837. Coverage varies by payer.

DSM-5-TR diagnostic criteria summary

Schizoaffective disorder requires:

An uninterrupted period of illness in which a major mood episode (major depressive or manic) occurs together with symptoms of schizophrenia.
Delusions or hallucinations for 2 weeks or more without a major mood episode, at some point in the lifetime course of the illness.
Mood episode symptoms for the majority of the total duration of the illness, including active and residual phases.
Not attributable to a substance or another medical condition.

DSM-5-TR names two types, which match the ICD-10-CM child codes: bipolar type when a manic episode is part of the presentation (F25.0), and depressive type when only major depressive episodes are part of it (F25.1).

Source: Keshavan, M. S. (2025). Schizoaffective disorder. Merck Manual Professional Edition, summarizing DSM-5-TR (American Psychiatric Association, 2022); Centers for Disease Control and Prevention / National Center for Health Statistics. ICD-10-CM Tabular List, FY2027.

The F25 codes

F25.0, Schizoaffective disorder, bipolar type. The tabular list includes cyclic schizophrenia and the manic and mixed types.
F25.1, Schizoaffective disorder, depressive type.
F25.8, Other schizoaffective disorders, a documented presentation with no specific code.
F25.9, Schizoaffective disorder, unspecified, including schizoaffective psychosis NOS.

Differential diagnosis

Schizophrenia (F20.-), psychosis without a concurrent major mood episode for most of the illness; F20 and F25 exclude each other.
Bipolar I Disorder (F31.-) and Major Depressive Disorder with psychotic features (F32.3, F33.3), psychosis only during mood episodes.
Unspecified Psychosis (F29), when psychosis is present but the record does not yet support a specific disorder.
Substance/medication-induced psychotic disorder, coded with the substance-specific codes in F10 to F19.
Psychotic disorder due to another medical condition (F06.0, F06.2).

Common comorbidities

Depression, substance use, and suicide risk call for regular screening alongside the psychotic symptoms. Use a depression measure such as the PHQ-9 for the depressive component, screen for alcohol use with the AUDIT, and code co-occurring conditions separately.

Documentation patterns

Initial visit: the psychotic symptoms observed, the mood episodes (type and dates), the period of psychosis without a mood episode, substance and medical workup, and the type that supports F25.0 or F25.1.
Follow-up visits: track psychotic and mood symptoms with the same clinician-rated scale, and update the subcode if a manic episode appears in a presentation coded as depressive type.

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Frequently asked questions

What is ICD-10 code F25?
F25 is the ICD-10-CM category for Schizoaffective disorders, in the F20 to F29 block (Schizophrenia, schizotypal, delusional, and other non-mood psychotic disorders). It is not billable on its own; claims use one of its four child codes, which name the type of mood episode.
Is F25 a billable ICD-10-CM code?
No. In the FY2027 ICD-10-CM code set (effective October 1, 2026), F25 is a category header. The billable codes are F25.0 (Schizoaffective disorder, bipolar type), F25.1 (Schizoaffective disorder, depressive type), F25.8 (Other schizoaffective disorders), and F25.9 (Schizoaffective disorder, unspecified).
What is the difference between F25.0 and F25.1?
F25.0 (bipolar type) is used when a manic episode is part of the presentation; major depressive episodes may also occur. The tabular list includes "Cyclic schizophrenia" and the manic and mixed types under F25.0. F25.1 (depressive type) is used when only major depressive episodes are part of the presentation.
When is F25.9 used?
F25.9 (Schizoaffective disorder, unspecified) is for schizoaffective disorder documented without the type; the tabular list includes "Schizoaffective psychosis NOS" under it, and the Alphabetic Index sends "Disorder, schizoaffective" with no further detail to F25.9. Under the official guidelines, F25.8 is for a documented presentation that has no specific code, and F25.9 is for one documented without that detail.
What are the diagnostic criteria for schizoaffective disorder?
A major mood episode (depressive or manic) occurs together with the symptoms of schizophrenia. Delusions or hallucinations must also be present for 2 weeks or more without a major mood episode at some point in the lifetime course, and symptoms of a major mood episode must be present for the majority of the total duration of the illness, including active and residual phases.
What is the difference between schizoaffective disorder and schizophrenia?
The Merck Manual distinguishes schizoaffective disorder from schizophrenia by the coexistence of a major depressive or manic episode. Category F20 (Schizophrenia) carries an Excludes1 note for schizoaffective disorder (F25.-), so the two are not coded together.
What is the difference between F25 and a mood disorder with psychotic features?
Category F25 carries an Excludes1 note for mood disorders with psychotic symptoms (F30.2, F31.2, F31.5, F31.64, F32.3, F33.3). In those disorders, psychosis occurs only during mood episodes. Schizoaffective disorder requires psychotic symptoms for at least 2 weeks without a mood episode. Telling them apart may require following the symptoms over time.
What scale is used with F25?
There is no single screening test that diagnoses schizoaffective disorder. Clinician-rated scales such as the Brief Psychiatric Rating Scale (BPRS) measure the breadth and severity of psychotic and mood symptoms and are useful for tracking change once care begins. A depression measure such as the PHQ-9 can track the depressive component.
How is schizoaffective disorder treated?
According to the Merck Manual, treatment combines antipsychotic and/or antidepressant medication, psychotherapy, and community support. For the bipolar (manic) type, a second-generation antipsychotic may be enough, with a mood stabilizer added if needed. For the depressive type, an antidepressant may be added once psychotic symptoms are stable, with SSRIs preferred for their safety profile.

Sources

1. 1.Centers for Disease Control and Prevention, National Center for Health Statistics. (2026). ICD-10-CM Tabular List of Diseases and Injuries, FY2027 (effective October 1, 2026).
2. 2.Centers for Disease Control and Prevention, National Center for Health Statistics. (2026). ICD-10-CM Official Guidelines for Coding and Reporting, FY2027, Section I.A.9.
1. 3.Keshavan, M. S. (2025). Schizoaffective disorder. Merck Manual Professional Edition.
2. 4.American Psychiatric Association. (2022). Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR).