MDQ Preliminary Assessment
Mood Disorder Questionnaire for Bipolar Disorder Screening
What is the MDQ?
The Mood Disorder Questionnaire (MDQ) is a validated self-report screening tool for bipolar disorder. Developed by Hirschfeld et al. (2000), it screens for a lifetime history of manic or hypomanic episodes by asking about 13 specific symptoms.
Frequently Asked Questions
What is a positive MDQ score?
The MDQ is positive when: (1) 7 or more of 13 symptom questions are answered 'Yes', AND (2) several symptoms occurred during the same period, AND (3) symptoms caused moderate or serious problems. All three criteria must be met.
What does the MDQ screen for?
The MDQ screens for bipolar spectrum disorder, including Bipolar I, Bipolar II, and cyclothymia. It was developed to identify patients who may have been misdiagnosed with unipolar depression.
Who developed the MDQ?
The MDQ was developed by Robert Hirschfeld, MD and colleagues, and validated in the American Journal of Psychiatry (2000). It demonstrated a sensitivity of 73% and specificity of 90% in a specialty bipolar outpatient clinic sample (PMID 11058490). Performance may be lower in primary care and general population settings, where bipolar prevalence is lower and false-positive rates are higher.
Can the MDQ miss bipolar II disorder?
The MDQ has lower sensitivity for bipolar II than bipolar I because hypomania symptoms are milder. A negative MDQ does not rule out bipolar II. Clinical interview remains essential for accurate diagnosis.
Should the MDQ replace a clinical interview?
No. The MDQ is a screening aid to facilitate clinical conversations about mood episodes. A positive screen should lead to a detailed psychiatric evaluation including detailed mood history and collateral information.
Understanding your results
For clinicians
Automate MDQ delivery, scoring, and longitudinal tracking across your patient panel. See how practices go live in 48 hours.
For individuals
This tool provides a preliminary screen only, not a substitute for clinical evaluation. Share your results with a qualified mental health professional for proper follow-up.
Learn more about Bipolar Disorder